Cisplatin diabetes
Web17 hours ago · Injectable cisplatin, methotrexate, and fluorouracil These generic drugs are widely used to treat common cancers in adults and children. Methotrexate treats acute lymphoblastic leukemia in... WebOct 6, 2016 · Cisplatin [Cis-diamminedichloroplatinum(II)] is the most nephrotoxic chemotherapeutic drug, discovered over four decades ago. Nephrotoxicity is the major side effect that limits the dose of cisplatin that can be safely administered, and it is a clinical problem in cancer patients who receive cisplatin combination chemotherapy.
Cisplatin diabetes
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WebDec 16, 2024 · Cisplatin (CDDP; cis-dichlorodiammine platinum [II]) is a non-specific drug of the cell cycle with strong cytotoxicity and broad-spectrum antitumor effects; it is widely used in urogenital system tumors, malignant lymphoma, breast cancer, head and neck cancer, non-small cell lung cancer, etc. ( 1 – 3) Cisplatin-induced nephrotoxicity is … http://mdedge.ma1.medscape.com/fedprac/article/227870/oncology/improving-ototoxicity-monitoring-cisplatin-therapy-va-northeast-ohio
WebFeb 21, 2024 · Our data show that the usage of DPP-4 inhibitors to diabetic-cancer patients could reduce the incidence of cisplatin-induced AKI from 64% to 25%, but its preventive … WebFeb 26, 2024 · severe or ongoing nausea and vomiting; vision problems, pain behind your eyes; hearing problems, ringing in your ears; pain, redness, swelling, or skin changes where the injection was given; bone ...
WebDec 3, 2024 · Cisplatin-based chemotherapy (CBCT) is part of standard treatment of several cancers. In testicular cancer (TC) survivors, an increased risk of developing metabolic syndrome (MetS) is observed. In this epigenome-wide association study, we investigated if CBCT relates to epigenetic changes (DNA methylation) and if epigenetic … WebApr 1, 2013 · Pathophysiology of Diabetes Insipidus (DI) DI is a clinical syndrome characterized by polyuria (due to a defect in the urinary concentrating mechanism) and compensatory polydipsia. In the general population, the prevalence of DI is approximately one per 25,000–30,000 ( 7 – 9 ).
WebBackground A strategy for preventing cisplatin nephrotoxicity due to enhanced oxidative stress and inflammatory response is highly desirable. Thioredoxin-1 (Trx), an endogenous redox-active protein,
WebApr 10, 2024 · Systemic therapy is considered standard of care for previously untreated BTC and often includes gemcitabine and cisplatin chemotherapy as established by the phase III ABC-02 trial. 7 A phase ... Comorbidity status was collected for diabetes, hypertension, dyslipidemia, chronic kidney disease, and CVD. The latter included arrhythmias ... granite city il tax assessorWebApr 5, 2024 · Poorly controlled diabetes (fasting blood glucose [FBG] > 10 mmol/L); ... Known hypersensitivity to active ingredients or excipients of the study drug, such as envafolimab and cisplatin; Subjects who have concomitant diseases that, in the investigator 's judgment, would seriously jeopardize the subject' s safety or affect the completion of … granite city il racewayWebFeb 1, 2016 · Request PDF Central Diabetes Insipidus and Cisplatin-Induced Renal Salt Wasting Syndrome: A Challenging Combination We describe a 2-year-old female with … granite city il teacher salaryWebMar 1, 2024 · Cisplatin is a well‐known chemotherapeutic agent that can be associated with hyponatremia. It is known to be associated with a multitude of renal disorders including acute kidney injury with reduced glomerular filtration, Fanconi syndrome, and renal tubular acidosis, nephrogenic diabetes insipidus and renal salt wasting syndrome. granite city il sales tax rateWebFeb 1, 2024 · Call your doctor right away if you have a rash, diarrhea, a fever or chills, hives, hoarseness, itching, lightheadedness or dizziness, trouble breathing, trouble swallowing, … granite city il school board membersWebFeb 1, 2016 · There are a lot of causes for water and electrolytic disturbances and, among them, transient diabetes insipidus (DI) has been found to be the most common followed by syndrome of inappropriate... chi ning company ltdWebMay 3, 2024 · Both diabetes and cancer are related to obesity, inflammation and increased blood sugar. Fortunately, the same steps that you take to manage your diabetes can also help lower your cancer risk and your risk for recurrence: Maintain a healthy diet. Fill two-thirds of your plate with vegetables, fruits and whole grains. granite city il rentals