Ctcf kda
WebBPTF plays an important role in regulating nucleosome occupancy at nucleosome-free regions (NFRs) at sites occupied by the multivalent factors CTCF and cohesin via direct interaction with CTCF and the cohesin subunit SA2. In addition, BPTF also interacts with c-MYC and plays an essential role in its genomic distribution and biological activity. WebA transcription factor is a protein that binds to specific DNA sequences ( enhancer or promoter), either alone or with other proteins in a complex, to control the rate of transcription of genetic information from DNA to messenger RNA by promoting (serving as an activator) or blocking (serving as a repressor) the recruitment of RNA polymerase.
Ctcf kda
Did you know?
WebMay 1, 2024 · The loss of CTCF poly ADP-ribosyltion in breast cancer leading to the expression of both 180-kDa and 130-kDa in comparison to only 180-kDa CTCF in normal breast tissues likely ... 2009). Although CTCF-130-kDa or Rb2/p130 can be used as the biomarker for the cancer progression, the utility of CTCF-130-kDa as the disease … WebSep 15, 2009 · Purpose: There is compelling evidence of a relationship between poly(ADP-ribosyl)ation and tumorigenesis; however, much less is known about the role of specific targets of poly(ADP-ribosyl)ation in tumor development. Two forms of the multifunctional transcription factor, CTCF, were previously identified: a 130-kDa protein (CTCF-130), …
WebFeb 27, 2024 · The 82 kDa CTCF protein is highly conserved in most bilateral animals and is ubiq-uitously expressed in the nucleus across all tissue types. Between its N-terminal and.
WebPolyclonal Antibody for studying CTCF. Cited in 67 publications. Validated for WB, IP, IF, ChIP. Highly specific and rigorously validated in-house, CTCF Antibody (CST #2899) is … WebJun 8, 2004 · The protein CTCF plays an essential role in the action of a widely distributed class of vertebrate enhancer-blocking insulators, of which the first example was found in a DNA sequence element, HS4, at the 5' end of the chicken beta-globin locus. ... a 38-kDa nucleolar phosphoprotein that is concentrated in nuclear matrix preparations. In this ...
WebCTCF has a predicted molecular weight of 84 kDa and CTCFL, 74 kDa. However, CTCF is known to migrate as a 130-kDa protein [39]. Since the transgenes are expressed as fusion proteins with FLAG tag...
WebJul 10, 2024 · Silver-stained SDS PAGE gel of IP proteins showing chicken CTCF protein of approximately 140 kDa, and lamprey CTCF protein of >250 kDa. Detailed procedures of western blotting and ... inyo county probation officeWebDepartment of Children and Families. 505 Hudson Street. Hartford CT 06106. Phone Number: 860-550-6300. E-mail the Commissioner. onrr lease cross referencehttp://www.zen-bioscience.com/prod_view.aspx?IsActiveTarget=True&TypeId=163&Id=430151&FId=t3:163:3 onrr lease numberWebApr 6, 2012 · Here, we report that regulation of CTCF by de-SUMOylation is dependent upon hypoxic and oxidative stresses. We found that stimulation of human corneal … inyo county property taxWebBackground Information. CTCF is a ubiquitous 11 zinc finger (ZF) protein with highly versatile functions. A transcriptional repressor, CTCF, binds to promoters of vertebrate c-myc gene. It also binds to the PLK and PIM1 promoters. CTCF may prevent the access of transcriptional activators to enhancers. onrr locationsWebMay 23, 2016 · The multidomain CCCTC-binding factor (CTCF), containing a tandem array of 11 zinc fingers (ZFs), modulates the three-dimensional organization of chromatin. We … onrr marketable conditionWebThe recombinant protein with a predicted molecular weight of 43.3 kDa was removed from the gel and purified by electroelution. The electroelution was conducted in cellulose tubes (Sanko Junyaku Co., Ltd., Tokyo, Japan) filled with an electroelution buffer (100 mM sodium phosphate and 0.1% SDS; pH 7.0) at 100 V and 100 mA for 17 h. onrrit