Phospho stat1
WebInvitrogen Anti-Phospho-STAT1 (Tyr701) Monoclonal (ST1P-11A5), Catalog # 33-3400. Tested in Western Blot (WB), Immunohistochemistry (Paraffin) (IHC (P)), ChIP assay … Phospho-Stat1 (Tyr701) (58D6) Rabbit mAb detects endogenous levels of Stat1 only when phosphorylated at tyrosine 701. The antibody detects phosphorylated tyrosine 701 of p91 Stat1 and also the p84 splice variant. It does not cross-react with the corresponding phospho-tyrosines of other Stat proteins. Species Reactivity: Human, Mouse
Phospho stat1
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WebMar 21, 2024 · STAT1 (Signal Transducer And Activator Of Transcription 1) is a Protein Coding gene. Diseases associated with STAT1 include Immunodeficiency 31C and Immunodeficiency 31B . Among its related pathways are IL-9 Signaling Pathways and Prolactin Signaling . Gene Ontology (GO) annotations related to this gene include DNA … WebNov 29, 2024 · IFN-I is the key regulatory component activating and modulating the response of innate and adaptive immune system to bacterial as well as viral pathogens. IFN-I promotes the expression of IFN-induced genes (ISG) and, consequently, the production of chemokines, e.g., CXCL10. Those chemokines control migration and localization of …
http://sigma-aldrich.cnreagent.com/pdetail407557.html WebCell-Based phospho-STAT ELISA Samper Kit for detecting phospho-STAT1 (pTyr 701), phospho-STAT3 (pTyr 705), and phospho-STAT5 (pTyr 694) in cultured cell lines 检测培养 …
WebMar 31, 2024 · STAT1 is localized predominantly in the cytoplasm prior to cytokine stimulation and upon receptor activation by IFNγ, the receptor-associated JAKs phosphorylate a critical tyrosine residue at position 701 in the STAT1 transactivation domain producing phosphorylated STAT1 (P-STAT1). WebThe Cell-Based phospho-STAT1 (pTyr701) ELISA kit is a very rapid, convenient, and sensitive assay kit that can monitor the activation or function of important biological pathways in cells. It can be used for measuring the relative amount …
WebSTAT1, also known as signal transduction and activator of transcription 1, is a ubiquitously expressed cytoplasmic protein and is activated in response to cytokine signaling, including IFN-α, IFN-γ, EGF, PDGF, and IL-6. Upon activation, STAT1 is phosphorylated at Tyrosine 701 (Tyr701) by receptor-associated kinases, including JAK1, JAK2, and TYK2. how to start with nerdy turtlesWebAnti-phospho-STAT1 (Tyr701) Antibody is a Rabbit Polyclonal Antibody for detection of phospho-STAT1 (Tyr701) also known as Transcription factor ISGF-3 components p91/p84 & has been validated in WB. Research Category Epigenetics & Nuclear Function. Research Sub Category Transcription Factors. how to start with microsoft teamsWebAug 15, 2024 · Membranes were then incubated overnight at 4°C with primary antibodies specific for p65, IκBα, IKKβ, phospho-IKKβ (Abcam, Cambridge, UK), phospho-Stat1 … react native this setstate multiple objectsWebSTAT1, also known as signal transduction and activator of transcription 1, is a ubiquitously expressed cytoplasmic protein and is activated in response to cytokine signaling, including IFN-α, IFN-γ, EGF, PDGF, and IL-6. how to start with mongodbWebPhospho-STAT1 regulates pro- and anti-apoptotic genes following several stress-induced responses. It interacts with p53 and promotes p53-mediated transcriptional gene activity and apoptosis. STAT1 is also an essential factor of stress-induced and DNA damage-induced checkpoint pathways and thus, acts as a tumor suppressor. 1 4 2. how to start with kafkaWebStat1 has two alternatively spliced isoforms, 91-kDa Stat1α and 84-kDa Stat1β; Stat1α has 38 additional C-terminal amino acids. In response to the binding of IFNα, IFNγ, EGF, PDGF, … react native theme providerWebSTAT1 is known to regulate several genes which are involved in cell growth, apoptosis, immune responses, and lipid metabolism. Further, STAT1 plays an important role in mediating cell viability in response to different cell stimuli and pathogen exposure. The STAT1 gene is located on chromosome 2. react native throw error