E3 ubiquitin-protein ligase MARCH5, also known as membrane-associated ring finger (C3HC4) 5, is an enzyme that, in humans, is encoded by the MARCH5 gene. It is localized in the mitochondrial outer membrane and has four transmembrane domains. See more Gene The human gene MARCH5, also known as MITOL or RNF153, has 7 Exons and locates at the chromosome band 10q23.32-q23.33. Protein See more As an E3 ubiquitin ligases, enzyme MARCH 5 catalyzes the transfer of ubiquitin from an E2 ubiquitin-conjugating enzyme to an identified protein substrate. MARCH5 was firstly identified as a See more Like the other MARCH and septin genes, care must be exercised when analyzing genetic data containing the MARCH5 gene in See more Considering that both Drp1 and MAP1B are substrates for MITOL, MITOL is thought to play a protective role against nitrosative stress-mediated disruption of mitochondrial … See more • Karbowski M, Neutzner A, Youle RJ (Jul 2007). "The mitochondrial E3 ubiquitin ligase MARCH5 is required for Drp1 dependent mitochondrial division". The Journal of Cell Biology. 178 (1): 71–84. doi:10.1083/jcb.200611064. PMC 2064424. PMID See more
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WebApr 15, 2015 · MARCH5, NT (MARCH5, RNF153, E3 ubiquitin-protein ligase MARCH5, Membrane-associated RING finger protein 5, Membrane-associated RING-CH protein V, … WebRNF153 is a reported alias of the human protein 'membrane associated ring-CH-type finger 5', encoded by the gene MARCHF5. Anti-RNF153 antibodies are available from several … WebIMPORTANT NOTE: NIH does not independently verify information submitted to the GTR; it relies on submitters to provide information that is accurate and not misleading.NIH … excel add title to each page